相关实验视频

Updated: Jun 21, 2026

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation
08:43

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation

Published on: May 31, 2016

19.6K

骨源PDGF-BB在雄性小鼠中驱动大脑血管化

Jiekang Wang1,2, Ching-Lien Fang1, Kathleen Noller2

  • 1Department of Orthopaedic Surgery.

The Journal of clinical investigation
|October 10, 2023
PubMed
概括

从骨细胞中提升的血小板衍生生长因子BB (PDGF-BB) 在老年雄性小鼠中驱动大脑血管化. 这一发现揭示了与年龄相关的大脑微血管变化的新机制.

关键词:
骨生物学 骨生物学 骨生物学微循环是一种微循环.神经系统疾病 神经系统疾病骨质细胞/骨质细胞生物学血管生物学 血管生物学

更多相关视频

Visualizing Angiogenesis by Multiphoton Microscopy In Vivo in Genetically Modified 3D-PLGA/nHAp Scaffold for Calvarial Critical Bone Defect Repair09:34

Visualizing Angiogenesis by Multiphoton Microscopy In Vivo in Genetically Modified 3D-PLGA/nHAp Scaffold for Calvarial Critical Bone Defect Repair

Published on: September 7, 2017

9.3K
Brain Pericyte Calcium and Hemodynamic Imaging in Transgenic Mice In Vivo14:22

Brain Pericyte Calcium and Hemodynamic Imaging in Transgenic Mice In Vivo

Published on: November 20, 2021

3.7K

相关概念视频

Regulation of Angiogenesis and Blood Supply01:24

Regulation of Angiogenesis and Blood Supply

Rapidly dividing tumors, embryos, and wounded tissues require more oxygen than usual, lowering the oxygen concentration in the blood. At low oxygen or hypoxic conditions, an oxygen-sensitive transcription factor called the hypoxia-inducible factor 1 or HIF1 is activated. HIF1 is a dimeric protein of alpha (ɑ) and beta (β) subunits.  Under optimal oxygen conditions, HIF1β is present in the nucleus while HIF1ɑ remains in the cytosol. HIF1ɑ is hydroxylated by prolyl hydroxylase and factor...