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Updated: Jul 14, 2025

A Mouse Model of Pulmonary Fibrosis Induced by Nasal Bleomycin Nebulization
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帕洛西丁通过阻断GRK2/Smad3通路来预防白血素诱导的肺纤维化

Kaochang Zhao1, Hanxiang Nie1, Zheng Tang2

  • 1Department of Respiratory and Critical Care Medicine, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, China.

Aging
|October 10, 2023
PubMed
概括

帕洛西丁 (PRXT) 通过抑制G蛋白结合受体激酶-2 (GRK2) 和肺纤维细胞中的Smad3激活,有效治疗肺纤维化. 这项研究表明,PRXT改善了小鼠的肺功能,并减少了小鼠的纤维化标志物.

关键词:
格鲁吉亚克朗2格鲁吉亚克朗2这真是太疯狂了肺部纤维细胞细胞.帕洛克塞提因 (paroxetine) 是一种药物.肺部纤维化 肺部纤维化

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