在妊娠期热囊细胞新生病患者中,艾滋病毒的高发病率
Victoria L Parker1, Zoe L I Baker1, Benjamin J Stone2
1Division of Clinical Medicine, School of Medicine and Population Health, University of Sheffield.
AIDS (London, England)
|October 10, 2023
概括
在患有孕期热囊细胞瘤 (GTN) 的患者中,艾滋病毒的患病率显著更高. 这项研究发现GTN患者的艾滋病毒阳性率为1.3%,这促使建议在专业中心进行普遍的艾滋病毒检测.
科学领域:
- 生殖医学 生殖医学
- 传染性疾病 传染性疾病
- 在瘤学瘤学.
背景情况:
- 妊娠热囊细胞瘤 (GTN) 是一种罕见的妊娠并发症.
- 了解艾滋病毒和GTN的同时发生对于患者管理和公共卫生至关重要.
- 关于GTN患者艾滋病毒患病率的先前数据有限.
研究的目的:
- 确定人类免疫缺陷病毒 (HIV) 在被诊断为妊娠期热瘤 (GTN) 的患者中的流行率.
- 为了将GTN患者的艾滋病毒患病率与该地区的普通人口进行比较.
主要方法:
- 在2015年至2021年期间,使用来自谢菲尔德热原体疾病中心 (STDC) 的数据进行了回顾性队列研究.
- 审查了3,591名怀孕期热囊细胞疾病 (GTD) 患者的病历,确定了221名为GTN治疗的患者.
- 分析了GTN患者的HIV检测率和阳性.
主要成果:
- 在221名GTN患者中,205人 (93%) 接受了艾滋病毒检测.
- 总共有3名患者 (1.3%) 呈艾滋病毒阳性,其中包括1名新诊断.
- 在GTN患者中,艾滋病毒的患病率为14:1000,大约是谢菲尔德和约克郡一般人口的7-9倍.
结论:
- 这项研究强调了GTN患者中艾滋病毒患病率大幅上升.
- 推对所有GTD和GTN患者进行常规的"选择退出"HIV检测,并将其转移到专业中心.
- 本建议旨在改善高风险人群中艾滋病毒的早期诊断和管理.
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