化脱酶2在缺血性心脏中保持线粒体功能:由硫素-1激活AMPK的氧依赖机制

Yi Zhu1, Ya-Jun He2,3, Yuan Yu3

  • 1Department of Anesthesiology, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

概括

脱酶2 (ALDH2) 通过激活AMPK信号,保护心脏免受缺血性损伤. 这种保护包括减少氧化应激,并通过Trx-1/AMPK-PGC-1α通路增强线粒体功能.

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