在COVID-19大流行期间接受怀孕期间的常规疫苗接种
Allison D Perelman1, Megan E Trostle2, Jillian Pecoriello1
1Department of Obstetrics & Gynecology, NYU Langone Health, New York, New York.
American journal of perinatology
|October 10, 2023
概括
在COVID-19大流行期间,孕妇更有可能接种流感疫苗,但结核病,白血病和百日咳 (Tdap) 疫苗率保持不变. 高风险群体,包括那些有公共保险或医疗并发症的人,疫苗接种率下降.
科学领域:
- 产科和妇科 产科和妇科
- 传染病流行病学 传染病流行病学
- 公共卫生 公共卫生
背景情况:
- 随着COVID-19大流行,日常医疗保健面临挑战,这可能会影响孕妇的疫苗接种率.
- 了解这一时期的疫苗接种趋势对于母婴健康至关重要.
- 评估对结核病,白血病和百日咳 (Tdap) 和流感的疫苗接种对于预防怀孕期间的传染病至关重要.
研究的目的:
- 为了将COVID-19大流行期间的产前Tdap和流感疫苗接种率与历史对照进行比较.
- 确定与疫情期间接种疫苗接受相关的人口和临床因素.
- 评估孕妇群体在接种疫苗方面的潜在差异.
主要方法:
- 采用了回顾性队列研究设计,将2020年9月至2021年1月的孕妇与前一年的历史队列进行比较.
- 数据包括人口统计,产前护理启动,保险状况和医疗并发症.
- 统计分析包括千平方测试,费舍尔的精确测试和多变量逻辑回归 (p < 0.05).
主要成果:
- 总的来说,孕妇在大流行期间更有可能接种流感疫苗 (aOR 1.7).
- 流行病和对照组之间的Tdap疫苗接受率相似 (aOR 1.5).
- 然而,在疫情期间,公共保险和医疗并发症的孕妇中,流感和Tdap疫苗的接种率显著下降.
结论:
- 虽然在COVID-19大流行期间整体流感疫苗接种增加,但Tdap疫苗接种率没有变化.
- 在高风险人群中观察到疫苗接种的显著差异,包括那些有公共保险和并发症的人群.
- 这些发现强调了有针对性的疫苗接种咨询和干预措施的必要性,以解决孕产妇免疫接种方面的不平等问题.
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