MIND饮食坚持与死亡率之间的关联:糖尿病和非糖尿病队列的见解
Yanjun Song1,2, Zhen'ge Chang3, Chenxi Song1,2
1Cardiometabolic Medicine Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, 167A Beilishi Road, Xi Cheng District, Beijing, 100037, China.
Nutrition & diabetes
|October 10, 2023
概括
坚持MIND饮食可显著降低2型糖尿病 (T2DM) 患者的全因和心血管死亡风险. 这种饮食方法有望改善T2DM患者的健康状况.
科学领域:
- 营养流行病学 营养流行病学
- 心血管健康 心血管健康
- 糖尿病管理 糖尿病管理
背景情况:
- 关于地中海饮食方法阻止高血压干预神经退行性延迟 (MIND) 饮食对2型糖尿病 (T2DM) 的保护作用的证据有限.
- 调查MIND饮食对T2DM患者死亡率的影响对于公共卫生至关重要.
研究的目的:
- 评估坚持MIND饮食与死亡率之间的关联.
- 具体评估对T2DM和没有T2DM的个体的影响.
主要方法:
- 一项队列研究分析了来自NHANES数据集的6887名参与者,其中包括1021名T2DM患者.
- MIND饮食的坚持是暴露,所有原因和心血管 (CV) 死亡是主要的结局.
- 随访时间中位数为10年,记录了1087例全因死亡和377例CV死亡.
主要成果:
- 在T2DM患者中,高MIND饮食坚持 (得分>8.0) 与显著降低全因 (HR 0.75) 和心血管死亡 (HR 0.50) 风险有关.
- 对于没有T2DM的人来说,高MIND饮食的坚持显示出所有原因死亡风险的显著降低 (HR 0.83),但不是心血管死亡.
- 使用了4.5-13的MIND得分范围,低粘附度的门值为≤8.0.
结论:
- 在T2DM患者中,MIND饮食与减少全因和心血管死亡率有关.
- 这些发现表明MIND饮食对管理T2DM和改善患者结果的潜在益处.
- 进一步的研究可以探索MIND饮食在糖尿病人群中神经退行性延迟中的作用.
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