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Updated: Jul 14, 2025

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通过RNF5对EphA2稳定性的下调限制了其在HER2-阴性乳腺癌中抑制瘤的功能

Xiaojuan Li1, Fan Wang2, Lu Huang2

  • 1College of Clinical Medicine, Hubei University of Chinese Medicine, Wuhan, 430061, Hubei, China.

Cell death & disease
|October 10, 2023
PubMed
概括

环指蛋白5 (RNF5) 向以弗林受体A2 (EphA2) 降解,抑制其在HER2-阴性乳腺癌中的瘤抑制作用. 抑制RNF5可以提高EphA2水平,从而改善患者的生存率.

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