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Updated: Jul 14, 2025

A High Throughput MHC II Binding Assay for Quantitative Analysis of Peptide Epitopes
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A High Throughput MHC II Binding Assay for Quantitative Analysis of Peptide Epitopes

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HLA3DB:对/HLA复合物的全面注释使得T细胞表位的盲目结构预测成为可能

Sagar Gupta1,2, Santrupti Nerli1, Sreeja Kutti Kandy1

  • 1Center for Computational and Genomic Medicine, Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.

Nature communications
|October 10, 2023
PubMed
概括

人类白细胞抗原 (HLA) 复合物的精确建模得到了RepPred的改进,RepPred是一种识别保存骨形状的新方法. 这促进了对免疫监测和抗原识别的理解.

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Personalized Peptide Arrays for Detection of HLA Alloantibodies in Organ Transplantation

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Antigens Involved in Adaptive Immunity01:26

Antigens Involved in Adaptive Immunity

An antigen is any substance the immune system identifies as foreign and potentially harmful to the body, prompting an immune response. Antigens have two functional properties: immunogenicity and reactivity. Immunogenicity is the ability of an antigen to stimulate a specific immune response. At the same time, reactivity describes the antigen's ability to react with the cells and antibodies produced in response to it.
Complete Antigens
Complete antigens possess both immunogenicity and...
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