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基于冠状动脉计算机断层扫描血管学和冠状动脉缓慢流动的定量表心脂肪组织之间的关系

Jing Tong¹, Gui-Guang Bei¹, Li-Bo Zhang¹

¹Department of Radiology, General Hospital of Northern Theater Command, 83 Wenhua Road, Shenyang, 110016, Liaoning Province, China.

BMC cardiovascular disorders

|October 10, 2023

概括

通过冠状动脉计算机断层扫描血管学 (CCTA) 测量出的心上脂肪组织 (EAT) 体积增加与冠状动脉慢流 (CSF) 有显著的关联. 这一发现表明,EAT量可能是识别CSF的有价值指标.

科学领域:

心脏病学心脏病学
医疗成像医学成像
放射学放射学是一门学科.

背景情况:

心脂肪组织 (EAT) 是围绕心脏的代谢活跃的内脏脂肪.
冠状动脉慢流 (CSF) 是冠状动脉微血管功能受损的标志物.
定量EAT和CSF之间的关系需要进一步调查.

研究的目的:

探索从冠状动脉计算机断层扫描血管学 (CCTA) 和冠状动脉缓慢流 (CSF) 衍生出的定量上心脂肪组织 (EAT) 体积之间的关联.

主要方法:

对85名冠状动脉狭窄率<40%的患者进行了回顾性分析.
使用CCTA半自动量化EAT数量.
根据心肌梗塞流量级的血栓溶解,将患者分为CSF和正常冠状动脉流量组.
多变量后勤回归和ROC曲线分析,以评估CSF的EAT体积的关系和诊断值.

主要成果:

与正常流量组 (101.87±18.56) 相比,患有CSF的患者表现出明显更高的EAT体积 (128.83±21.59毫升).
EAT体积独立地与脑脊液相关 (OR=4.82,P<0.001).
在识别CSF时,EAT体积的ROC曲线下的面积为0.86,最佳切线为118.46mL,提供80%的灵敏度和94%的特异性.

结论:

通过CCTA量化的EAT体积增加与冠状动脉缓慢流动密切相关.
这项研究强调了EAT体积作为CSF的非侵入性标记物的潜在诊断价值.
需要进行更大规模的研究来证实这些初步发现,并确定EAT体积在CSF评估中的作用.

关键词:

冠状动脉计算机断层扫描血管图谱.冠状动脉的缓慢流动胸前脂肪组织的副心脏脂肪组织.

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