预防性抗生素在带有鼻内隔膜支架的血栓整形中:一个比较分析
Ofir Zavdy1,2, Gabriel Nakache2,3, Uri Alkan1,2
1Department of Otolaryngology, Head and Neck Surgery, Rabin Medical Center, Petach Tikva, Israel.
概括
手术后的抗生素治疗可能会降低带有阴道内线 (ISS) 的血栓整形术后的感染风险. 不接受抗生素治疗的患者感染率更高,这表明潜在的预防益处.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 手术感染预防 手术感染预防
- 微生物学 微生物学
背景情况:
- 术后抗生素的使用是常见的,后septoplasty与脑内骨 (ISS),尽管有限的支持证据.
- 在这些程序中调查抗生素治疗的必要性和有效性至关重要.
研究的目的:
- 为了评估抗生素治疗在预防手术后感染的作用,以国际空间站放置的血栓形成术后.
- 在这个患者队列中确定与术后感染相关的风险因素.
主要方法:
- 在成年患者接受ISS血栓整形手术的回顾性比较研究中,有或没有轮减少.
- 分析电子健康记录,包括鼻腔培养和检查ISS的细菌存在.
- 统计分析以确定抗生素和其他因素对感染率的影响.
主要成果:
- 整体术后感染率较低 (6%),与之前的研究一致.
- 不接受抗生素治疗的患者的感染率显著增加 (OR=8.2,p=0.01).
- 糖尿病 (OR=5.2,p=0.032) 和手术前检测Klebsiella pneumoniae (OR=16.6,p=0.001) 是感染的重要危险因素.
结论:
- 使用ISS的分管整形增加了格拉姆阴性细菌殖民和鼻子感染的风险.
- 静脉注射抗生素的单次手术前剂量可能是ISS形术的有益的预防策略.
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