引入冷藏血小板的运营影响
John T Blake1,2, Elizabeth Krok3, Katerina Pavenski3
1Industrial Engineering, Dalhousie University, Halifax, Nova Scotia, Canada.
Transfusion
|October 11, 2023
概括
保持冷储血小板 (CSP) 和室温血小板 (RTP) 的双重库存可能不会显著减少整体血小板浪费. 虽然CSP为创伤提供了临床益处,但它增加了浪费,而RTP浪费的减少是最小的.
科学领域:
- 输血医学 输血医学
- 血液学 血液学 血液学
- 血液银行业务 血液银行业务
背景情况:
- 冷储血小板 (CSP) 增强凝血的启动,对活跃出血的患者有益.
- 室温血小板 (RTP) 是在预防性输血中增加血小板数量的首选方法.
- 由于潜在的浪费,双重库存系统 (RTP和CSP) 的经济可行性是不确定的.
研究的目的:
- 评估双重血小板清单系统对血小板浪费的影响.
- 确定CSP的好处是否超过运营成本和浪费影响.
- 评估在区域血液供应中管理RTP和CSP的策略.
主要方法:
- 开发了一个区域血液供应和病例医院操作的模拟模型.
- 两个场景进行了比较:"没有CSP" (仅RTP) 和"CSP" (RTP和CSP).
- 在"CSP"情景中,策略包括在现场将RTP转换为CSP,并接收预先转换的CSP.
主要成果:
- 由于在现场血小板年龄的限制,集中CSP供应至关重要.
- 增加CSP库存减少了产品短缺,但增加了CSP浪费.
- 在现场进行RTP转换是有限的,因此在引入CSP时,RTP浪费的减少是最小的.
结论:
- 由于其在创伤中的临床疗效,CSP是血液银行配方的宝贵补充.
- 随着CSP库存的实施,RTP浪费的显著减少不太可能.
- 双重库存系统的运营开销需要仔细考虑潜在的浪费利益.
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