糖尿病肺病 - 一种新的糖尿病相关并发症:病理生理学,潜在机制和组合药物治疗
Jyotsana Dwivedi1, Pranay Wal1, Biswajit Dash2
1PSIT- Pranveer Singh Institute of Technology (Pharmacy), Kanpur, India.
Endocrine, metabolic & immune disorders drug targets
|October 11, 2023
概括
糖尿病显著影响肺部健康,加速呼吸系统衰退. 这篇评论强调了"糖尿病肺部"及其相关的肺部疾病,强调了进一步研究糖尿病引起的肺功能障碍的必要性.
科学领域:
- 内分泌学和肺病学 肺病学
- 代谢和呼吸系统医学
背景情况:
- 肺部越来越被认为是糖尿病的目标器官.
- 糖尿病与肺透气,支气管运动调度,肺体积和神经上腺体内膜异常有关.
研究的目的:
- 审查有关糖尿病肺病症及其病理生理学的现有文献.
- 总结与1型和2型糖尿病相关的肺部疾病.
主要方法:
- 在主要的科学数据库 (PubMed,Scopus,ScienceDirect等) 进行全面的电子搜索. ) 的情况.
- 包括1978年至2023年间发表的评论文章.
- 关键词包括"糖尿病"",糖尿病性肺病"",病理生理学"",肺部疾病"和"肺部感染".
主要成果:
- 全球糖尿病发病率正在上升,这对公众健康构成了重大挑战.
- "糖尿病肺"可能呈现加速衰老,呼吸功能下降的速度比非糖尿病患者快2-3倍.
- 糖尿病与肺纤维化有关,尽管因果关系需要进一步调查.
结论:
- 由于不清楚的因果关系和细胞变化,糖尿病诱导的肺功能障碍未被充分认识到.
- 虽然糖尿病可以影响肺部疾病机制,但高血糖症与肺纤维化有关.
- 需要进一步的研究,以充分理解和解决与糖尿病相关的肺部并发症.
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