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卡姆雷利祖马布诱导的口服液化物反应与亚皮质CD4+T细胞透

Xiangjian Wang¹, Tao Fu², Weilian Sun¹

¹Department of Oral Medicine, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China.

Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners

|October 11, 2023

概括

卡姆雷利祖马布是一种抗PD-1抗体,可以引起罕见的口服液化物反应 (OLR). 这一案例表明CD4+T细胞,而不是CD8+细胞,可能在camrelizumab诱导的OLR病变发生中发挥作用.

科学领域:

在瘤学瘤学.
免疫学免疫学免疫学
皮肤病学皮肤病学

背景情况:

卡姆雷利祖马布是一种用于各种癌症的抗编程细胞死亡-1 (PD-1) 抗体.
与免疫相关的不良事件,特别是CD4+ T细胞介导反应,在使用PD-1抑制剂时越来越多地报告.
口腔状体反应 (OLR) 是抗PD-1疗法的罕见副作用,通常涉及CD8+T细胞.

关键词:

在CD4+ T细胞中.卡姆雷利兹马巴姆 (Camrelizumab) 是一个癌症免疫疗法免疫疗法与免疫相关的不良事件.口服液化物反应是一种口服液化物反应.

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