在COVID 19疫苗接种后乱的肝功能测试:与文献审查的罕见演示
Salma Salman1, Tayyab Khan1, Sadia Iqbal1
1Department of Medicine, Dow University of Health Sciences, Ojha Campus, Karachi,Pakistan.
JPMA. The Journal of the Pakistan Medical Association
|October 11, 2023
概括
巴基斯坦首例疫苗引发的肝功能障碍病例报告涉及一名接受西诺法姆COVID-19疫苗的医疗保健工作者. 经过彻底的调查,患者经历了延迟但完全的康复.
科学领域:
- 疫苗学 疫苗学 疫苗学
- 肝病学 肝病学是一种肝病学.
- 公共卫生 公共卫生
背景情况:
- 在全球范围内,COVID-19大流行促使疫苗的快速开发和部署.
- 巴基斯坦优先考虑医疗保健专业人员进行早期疫苗接种,其中Sinopharm是第一个可用的疫苗.
- 虽然通常是安全的,但疫苗接种后的不良事件需要持续监测.
研究的目的:
- 报告巴基斯坦首例疫苗引发的肝功能测试异常的记录病例.
- 为了突出与COVID-19疫苗接种相关的罕见不良事件.
- 为了强调差异诊断在肝功能障碍病例中的重要性,疫苗接种后进行肝功能测试.
主要方法:
- 一位女性医疗保健专业人员的案例报告.
- 详细的临床评估和实验室检查乱的肝功能测试.
- 排除肝酶升高的其他潜在原因.
主要成果:
- 患者在西诺法姆COVID-19疫苗接种后出现了乱的肝功能测试.
- 肝酶异常的发病时间延迟.
- 患者在没有针对肝功能障碍的特殊干预的情况下完全康复.
结论:
- 接种COVID-19疫苗,特别是Sinopharm疫苗,可能与短暂的,疫苗引发的肝功能测试异常有关.
- 接种疫苗后经历肝功能乱测试的医疗保健专业人员需要全面的检查,以排除其他病因.
- 这一案例强调了对新型疫苗的警药监的重要性.
相关概念视频
Diseases of the Liver and Gallbladder
589
Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
589
Esophageal Varices-II: Clinical Features and Management
74
Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
74
Liver Physiology
593
The liver, an essential organ in the human body, performs over 200 vital functions that can be broadly categorized into metabolic, hematological, endocrine regulation, and bile production.
Metabolic Regulation:
The liver is the central organ involved in regulating blood composition. It stabilizes blood glucose levels, maintaining them within the range of 70–110 mg/dL. When these levels drop, the liver breaks down glycogen reserves and releases glucose into the bloodstream. It can...
Metabolic Regulation:
The liver is the central organ involved in regulating blood composition. It stabilizes blood glucose levels, maintaining them within the range of 70–110 mg/dL. When these levels drop, the liver breaks down glycogen reserves and releases glucose into the bloodstream. It can...
593
Myocarditis II: Clinical Features and Diagnostic Tests
12
Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
12
Pericarditis II: Clinical Features and Diagnostic Tests
9
Pericarditis is distinguished by inflammation of the pericardium, the fibrous sac that encases the heart. It can be acute, lasting less than six weeks, or chronic, persisting for over three months. Understanding its clinical manifestations and diagnostic findings is crucial for timely and effective management.Clinical ManifestationsWhile pericarditis can be asymptomatic, it usually presents with characteristic symptoms such as:Chest Pain: The most characteristic symptom of pericarditis is chest...
9
Gastritis III: Clinical Manifestations and Management
307
The clinical manifestations of gastritis can vary depending on the cause and type of gastritis, but some common symptoms may include the following.
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
307


