一个儿童的泛耐药沙门氏菌血清型血栓炎症:一个病例报告
Nida Safdar1, Nasrullah Malik1, Summiya Nizamuddin1
1Department of Microbiology, Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, Pakistan.
JPMA. The Journal of the Pakistan Medical Association
|October 11, 2023
概括
广泛耐药的沙门氏菌 (XDR S. Typhi) 是一个不断增长的威胁. 这一案例突出了一个患有复发型伤寒的儿童,该儿童对梅罗和阿齐思罗辛等关键抗生素产生了耐药性.
科学领域:
- 传染性疾病 传染性疾病
- 微生物学 微生物学
- 公共卫生 公共卫生
背景情况:
- 由于沙门氏菌 (Salmonella enterica serovar Typhi) 引起的伤寒热,是全球重要的健康问题,特别是在资源较低的环境中.
- 获得清洁水和卫生设施的限制加剧了伤寒的传播.
- 巴基斯坦出现广泛耐药的沙门氏菌 (XDR S. Typhi) 构成了严重的公共卫生挑战.
研究的目的:
- 报告小儿病患中出现复发型伤寒病例.
- 为了描述沙门氏菌Typhi分离的抗微生物耐药性概况.
主要方法:
- 一个患有复发性发烧疾病的儿童的临床病例陈述.
- 微生物学调查,包括对沙门氏菌的隔离和抗微生物敏感性测试.
主要成果:
- 这个孩子经历了伤寒发烧的复发.
- 致病的沙门氏菌Typhi分离物表现出对美罗烯和亚齐菌素的耐药性,这表明XDR S. Typhi.
结论:
- 这一案例凸显了 XDR S. Typhi 在儿童群体中日益增加的威胁.
- 耐美罗和阿兹胺素的耐药性凸显了迫切需要新的治疗策略和加强对台风的监测.
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