2型糖尿病抵抗训练的剂量反应关系:随机对照试验的元分析
Wanying Su1, Meiyi Tao2, Lin Ma3
1Joint Surgery and Sport Medicine Department, Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University), Changsha, Hunan, China.
Frontiers in endocrinology
|October 11, 2023
概括
抵抗训练 (RT) 在2型糖尿病 (T2DM) 患者中显著降低了糖化血红蛋白 (HbA1c) 和快速血糖 (FBG). 最佳的RT包括12-16周的持续时间,70-80%的1RM强度,每周2-3次,每组8-10次重复.
科学领域:
- 运动生理学 运动生理学
- 代谢疾病 代谢疾病
- 临床研究 临床研究
背景情况:
- 2型糖尿病 (T2DM) 占全球糖尿病病例的90%左右.
- 抵抗训练 (RT) 被认为具有降低T2DM中HbA1c和FBG的潜力.
- 对T2DM管理的最佳RT参数需要进一步研究.
研究的目的:
- 在T2DM患者中对RT对HbA1c和FBG的影响进行元分析.
- 为了确定RT变量 (持续时间,频率,强度) 的剂量反应关系.
- 检查随机对照试验 (RCT) 报告HbA1c和FBG减少的数据.
主要方法:
- 在主要的科学数据库中进行了全面的文献搜索,截至2023年2月.
- 使用物理治疗证据数据库 (PEDro) 标准评估研究质量.
- 使用Stata 16进行的元分析,包括26个RCT与1336名参与者.
主要成果:
- 与对照组相比,RT显著降低了HbA1c和FBG水平 (P<0.05).
- 每组重复次数是RT对HbA1c有效性的重要预测指标 (p=0.034).
- 观察到的最大减少时间为12-16周,70-80%的1RM强度,每周2-3次,每周8-10次重复, <60秒休息.
结论:
- 在T2DM患者中,RT对HbA1c和FBG产生有益影响.
- 确定关键培训参数可以提高RT的有效性.
- 研究结果为设计用于T2DM管理的RT计划的临床医生提供了参考.
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