化学和电外科手术对异位的有效性:系统性审查
Prasetyadi Mawardi1, Lian Kamilah1, Fanny Fauziyyah Heryadi1
1Department of Dermatology and Venereology, Faculty of Medicine, Sebelas Maret University/Dr Moewardi General Hospital, Surakarta, Indonesia.
Clinical, cosmetic and investigational dermatology
|October 11, 2023
概括
与三乙酸 (TCA) 治疗相比,电外科提供更高的治愈率和更低的异位复发率 (AGW). 然而,电外科手术带有出血和痕等风险,同时存在高风险的人类乳头瘤病毒 (HPV) 感染.
科学领域:
- 皮肤病学 皮肤病学
- 传染性疾病 传染性疾病
- 手术瘤学手术瘤学
背景情况:
- 异位 (AGW) 是一种常见的性传播感染 (STI),由人乳头瘤病毒 (HPV) 引起.
- 目前对AGW的治疗方法往往具有低清除率和高复发率.
- 用三乙酸 (TCA) 进行化学烧伤和电外科手术经常用于以最小的严重副作用去除AGW病变.
研究的目的:
- 系统地审查和比较化学烧结与TCA和电外科手术治疗AGW的疗效.
- 根据可用的临床试验和病例系列来评估治愈率和复发率.
主要方法:
- 按照PRISMA指南进行了系统审查.
- 从2013年1月到2023年3月,在PubMed和Cochrane图书馆进行了文献搜索.
- 包括13项研究 (7项关于TCA,6项关于电外科手术).
主要成果:
- 电外科证明了100%的治愈率,而TCA实现了94.1%的治愈率.
- 随访1年后的复发率在电外科手术 (14.6%) 与TCA (27.6%) 相比较较低.
- 电外科手术报告的副作用包括出血和痕形成.
结论:
- 电外科手术在AGW治疗中比TCA烧结更有效,提供更高的治愈率和更低的复发率.
- 尽管电外科手术的疗效很高,但它存在风险,包括出血,痕和HPV感染的高风险.
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