450名悬挂引起心脏骤停的患者的流行病学和结果预测因素:一项回顾性研究
Marie Salvetti1, Guillaume Schnell2, Nicolas Pichon3,4
1Medical-Surgical Intensive Care Unit, Centre Hospitalier de Versailles-Site André Mignot, Le Chesnay, France.
Frontiers in neurology
|October 11, 2023
概括
自杀死心脏骤停后生存的预测因素包括自发循环 (ROSC) 恢复的时间,血糖,乳酸水平和格拉斯哥昏迷表得分. 这些因素可以指导高风险患者的治疗.
科学领域:
- 紧急医疗 紧急医疗
- 心脏病学 心脏病学
- 毒理学 毒理学 毒理学
背景情况:
- 心脏骤停是吊死自杀企图的一个关键并发症.
- 关于这些病例的生存特征和预测因素的数据有限.
研究的目的:
- 为了确定因自杀性死而导致心脏骤停的患者的住院死亡率相关的因素.
- 为这种高风险患者群体提供治疗策略的信息.
主要方法:
- 这是一项回顾性,观察性,多中心的研究,涉及31家医院.
- 对连续入院的成年患者进行分析,这些患者因自杀性死而心脏骤停.
- 用多种归算的多变量逻辑回归来识别死亡率预测因子,并根据时间趋势进行调整.
主要成果:
- 在450名患者中,有18%的患者存活到出院.
- 死亡率的关键预测因素包括:自发循环恢复 (ROSC) 延长时间 (>20分钟),血糖升高 (>1.4 g/L) 和高乳酸水平 (>3.5 mmol/L).
- 住院时格拉斯哥昏迷量表 (GCS) 较高的分数 (>5) 与生存率的增加有关.
结论:
- 到ROSC的时间,入院血糖,动脉乳酸水平和昏迷深度是悬挂诱导心脏骤停生存的独立预测因素.
- 识别这些风险因素可以帮助临床决策,为患有高死亡风险的患者.
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