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水下与结直肠病变的常规内镜粘膜切除:随机对照试验的更新元分析

Aneesa Rahman Chowdhury¹, Jin Sun Kim¹, Mimi Xu¹

¹Division of Gastrointestinal and Liver Diseases, University of Southern California, Los Angeles, United States.

Endoscopy international open

|October 11, 2023

概括

与传统方法相比,水下内镜粘膜切除 (UEMR) 为结直肠病变提供了更好的块切除率. 这种技术是有效和安全的,没有增加手术时间或不良事件.

科学领域:

胃肠病学胃肠病学
手术瘤学手术瘤学
内镜手术进行内镜手术

背景情况:

结肠直肠癌是全球死亡的一个重要原因.
传统的内镜粘膜切除 (CEMR) 需要注射液体来切除多.
水下内镜粘膜切除 (UEMR) 使用水浸,省略注射.

研究的目的:

为了比较UEMR与CEMR在结直肠病变切除中的安全性和有效性.
综合这些内镜技术的最新证据.

主要方法:

在PubMed,Embase和Cochrane图书馆的系统文献搜索.
包括七项随机对照试验 (RCT),比较UEMR和CEMR.
主要结果:整体切除率;次要结果:复发,手术时间,不良事件.

主要成果:

与CEMR相比,UEMR的块切除率显著更高 (RR 1.18 [1.03, 1.35]).
两种方法之间在手术时间,复发率或不良事件方面没有发现显著差异.
分析包括来自7个RCT的数据,包括1581个多.

结论:

结肠直肠雷射是切除结肠直肠病变的有效和有前途的技术.
证据表明,UEMR可以提高块切除率,而不会影响安全性或效率.
在内镜断层切除中,UEMR是CEMR的可行的替代方案.

关键词:

结肠直肠癌是一种癌症.内镜切除 (多眼切除,ESD,EMRc,等等) 的方法内镜下部肠道管道下部肠道管道多胞胎 / 腺瘤 / ...

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