更年期妇女的大脑体积变化及其与认知功能的关联:结构化综述
Nur Zuliani Ramli1,2, Mohamad Fairuz Yahaya3, Nur Azlina Mohd Fahami4
1Department of Biochemistry, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.
Frontiers in aging neuroscience
|October 11, 2023
概括
更年期可能会增加神经系统症状,如认知能力下降. 研究表明,像海马体和额叶皮层等区域的大脑体积的变化与绝经后妇女的记忆缺陷有关.
科学领域:
- 神经科学是一个神经科学.
- 内分泌学 在内分泌学.
- 放射学 放射学是一门学科.
背景情况:
- 更年期过渡与潜在的神经症状有关,包括认知能力下降.
- 更年期期间的荷尔蒙变化可能会影响对认知功能至关重要的大脑结构.
研究的目的:
- 审查使用磁共振成像 (MRI) 检查更年期后大脑体积差异的研究.
- 为了将观察到的大脑结构变化与绝经后妇女的认知功能相关联.
主要方法:
- 进行了结构化的文献综述.
- 在Medline (Ovid) 和Scopus数据库中进行了搜索.
- 分析了符合纳入标准的14项研究.
主要成果:
- 大脑体积差异最常见于额叶和皮以及海马.
- 这些大脑区域对于记忆和更高的认知任务至关重要.
- 绝经后妇女的言语和视觉空间记忆减少与较小的区域大脑体积相关.
结论:
- 更年期与大脑的结构性变化有关,特别是在与记忆相关的区域.
- 这些变化与在绝经后妇女中观察到的认知缺陷相关.
- 需要进一步研究更大的样本大小和纵向设计来证实这些发现.
更多相关视频
07:30Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions
Published on: April 23, 2021
3.0K
12:50Lesion Explorer: A Video-guided, Standardized Protocol for Accurate and Reliable MRI-derived Volumetrics in Alzheimer's Disease and Normal Elderly
Published on: April 14, 2014
40.3K
相关概念视频
Menopause
178
Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...
178
Cognitive Development During Adulthood
126
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
126
