异型呈现的急性心周炎二次性至全源性血造干细胞移植:一个案例报告
Sourabh Goyal1, Angela Khidhir1, Matthew D Burwinkel1
1Department of Medicine, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, Buffalo, USA.
Cureus
|October 11, 2023
概括
急性心膜炎是一种罕见且可能致命的并发症,可在造血干细胞移植 (HSCT) 后早期发生. 早期诊断和治疗对于患者的治疗结果至关重要.
科学领域:
- 心脏病学 心脏病学
- 血液学 血液学 血液学
- 在瘤学瘤学.
背景情况:
- 心脏毒性是血造干细胞移植 (HSCT) 后的已知风险,通常在移植后100天内表现出来.
- 常见的原因包括移植对宿主疾病和调节方案 (化疗/辐射).
研究的目的:
- 报告一种罕见的急性心膜炎病例,该病例发生在异性HSCT后立即发生.
- 强调在HSCT接受者早期心脏评估的重要性.
主要方法:
- 一个60岁的女性患有AML后异构HSCT的病例介绍,表现为胸痛.
- 诊断工作包括心电图 (ECG) 和胸前心脏回声图.
- 治疗涉及高剂量静脉注射甲基prednisolone与一个逐渐缩小.
主要成果:
- 患者在移植后的早期阶段出现了急性心周炎与心周溢出.
- 症状消失了,并通过皮质类固醇治疗解决了输液.
- 确诊了急性心周炎的诊断.
结论:
- 急性心膜炎是一种罕见但严重的HSCT并发症,需要及时治疗.
- 这一案例凸显了在移植前阶段对高风险患者进行心脏风险分层和密切监测的必要性.
更多相关视频
11:55Induction of Alloantigen-specific Anergy in Human Peripheral Blood Mononuclear Cells by Alloantigen Stimulation with Co-stimulatory Signal Blockade
Published on: March 14, 2011
14.6K
09:25An Immunological Model for Heterotopic Heart and Cardiac Muscle Cell Transplantation in Rats
Published on: May 8, 2020
7.9K
相关概念视频
Pericarditis I: Introduction
11
Pericarditis is defined as the inflammation of the pericardium, the thin, sac-like membrane surrounding the heart. This condition can cause significant chest pain and other symptoms, often necessitating medical intervention. The pericardium has two layers: the inner visceral layer and the outer parietal layer, separated by a small amount of fluid that reduces friction during heartbeats.Types of PericarditisPericarditis can be classified into several types based on the duration and nature of the...
11
Pericarditis II: Clinical Features and Diagnostic Tests
9
Pericarditis is distinguished by inflammation of the pericardium, the fibrous sac that encases the heart. It can be acute, lasting less than six weeks, or chronic, persisting for over three months. Understanding its clinical manifestations and diagnostic findings is crucial for timely and effective management.Clinical ManifestationsWhile pericarditis can be asymptomatic, it usually presents with characteristic symptoms such as:Chest Pain: The most characteristic symptom of pericarditis is chest...
9
Pericarditis III: Medical Management
13
The primary objectives of managing pericarditis are to determine the underlying cause, provide effective therapy for treatment and symptom relief, and promptly detect signs and symptoms of cardiac tamponade. The following outlines the essential aspects of medical management for pericarditis:ObjectivesDetermine the Cause: Identifying the underlying cause of pericarditis is crucial for targeted treatment. Causes include viral infections, autoimmune diseases, post-cardiac injury syndrome, and...
13
