在急性缺血性中风患者中,血压变化和深度大脑微出血之间的相关性
Yaya Bao1, Jiayi Gu2, Tian Lv3
1Department of Neurology, Shaoxing University School of Medicine, Shaoxing, China.
Folia neuropathologica
|October 11, 2023
概括
夜间透静血压标准偏差 (NDBP-SD) 是急性缺血性中风患者严格深度大脑微出血 (CMB) 的重要指标. 较高的NDBP-SD水平可能会增加患上这些微型血液的风险.
科学领域:
- 神经学 神经学
- 心脏病学 心脏病学
- 放射学 放射学是一门学科.
背景情况:
- 急性缺血性中风对健康构成重大风险.
- 大脑微型出血 (CMBs) 越来越多地被认为是并发症.
- 了解导致CMBs的因素对于患者管理至关重要.
研究的目的:
- 在急性缺血性中风患者中分析24小时的门诊血压模式.
- 为了研究血压变化和严格的深层CMB之间的关系.
- 确定严格深层CMB的预测标记.
主要方法:
- 对131名急性缺血性中风患者的回顾性分析.
- 24小时门诊血压监测. 24小时门诊血压监测.
- 用于CMB检测和分类的磁感应度加权成像.
- 后勤回归和ROC曲线分析.
主要成果:
- 患有严格深度CMB的患者表现出更高的夜间透析血压标准偏差 (NDBP-SD).
- NDBP-SD被确定为严格深层CMB的一个独立风险因素 (OR=1.205,p=0.038).
- 7.81的NDBP-SD值显示了严格深层CMB的显著预测价值 (OR=3.872,p=0.012).
结论:
- 升高的NDBP-SD是急性缺血性中风中严格深层CMB的独立风险因素.
- 超过7.81的NDBP-SD可能会促进严格深层CMBs的发展.
- 门诊血压监测,特别是NDBP-SD,可以帮助CMB风险分层.
更多相关视频
相关概念视频
Ischemic Stroke ll: Pathophysiology
An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...
Hemorrhagic Stroke l: Introduction
A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
Hemorrhagic Stroke ll: Pathophysiology
A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...


