全球流行病学趋势和胆囊癌负担的变化
Srineil Vuthaluru1, Prateek Sharma1, Sanjib Chowdhury1
1Department of Surgery, Division of Surgical Oncology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Journal of surgical oncology
|October 11, 2023
概括
胆囊癌 (GBC) 负担在全球范围内不断增加,亚洲和拉丁美洲的发病率更高. 这种致命的癌症不成比例地影响女性和中等HDI国家,预计到2040年将大幅增加.
科学领域:
- 在瘤学瘤学.
- 流行病学 流行病学
- 全球健康 全球健康
背景情况:
- 胆囊癌 (GBC) 是一种罕见的致命恶性瘤,预后不佳.
- 在GBC发病率和死亡率方面存在显著的区域和人口差异.
- 了解全球趋势对于有效的公共卫生战略至关重要.
研究的目的:
- 分析全球胆囊癌的负担和趋势.
- 检查基于地理,社会经济发展 (人类发展指数 - HDI) 和性别的变化.
- 预测未来的GBC趋势到2040年.
主要方法:
- 使用了GLOBOCAN 2020数据库来获取GBC发病率和死亡率数据.
- 分析了从2020年到2040年的数据.
- 按地理区域,人类发展指数和性别进行分层分析.
主要成果:
- 亚洲,特别是印度和中国,承担了最高的绝对GBC负担.
- 拉丁美洲 (玻利维亚,智利) 和东南亚 (孟加拉国,尼泊尔) 的年龄标准化率最高.
- 中等的HDI国家比非常高的HDI国家死亡率更高;女性表现出更大的偏好.
- 预计到2040年,全球GBC负担将显著上升,区域和人口统计学变化.
结论:
- 全球GBC的负担将在未来二十年内大幅增加.
- 显著的区域和人口变化需要定制的干预措施.
- 调查结果将为解决这种致命恶性瘤的政策制定提供信息.
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