使用多模式神经成像来描述婴儿的社会大脑专业化
Maheen Siddiqui1, Paola Pinti1, Sabrina Brigadoi2,3
1Centre for Brain and Cognitive Development, Birkbeck, University of London, London, United Kingdom.
eLife
|October 11, 2023
概括
新的工具可以同时测量婴儿的大脑活动. 婴儿的社会处理在形形结节显示了协调的大脑反应,突出显示了早期的功能专业化.
科学领域:
- 神经科学是一个神经科学.
- 发育神经科学的发展神经科学.
- 认知神经科学 认知神经科学
背景情况:
- 由于单个成像方法的局限性,婴儿大脑的功能专业化是不太了解的.
- 现有的研究重点是神经或血液动力学活动的孤立的空间或时间方面.
- 协调的生理反应,包括血液动力学和代谢变化,被假设为功能专业化的基础.
研究的目的:
- 开发用于同时测量清醒婴儿的神经活动 (EEG),代谢率和血液氧化 (宽带近红外光谱) 的新型工具.
- 研究婴儿大脑在社会处理过程中的功能专业化的发展.
- 探索神经活动和早期发育中的血液动力学/代谢变化之间的关系.
主要方法:
- 在4至7个月大的婴儿同时进行多模式神经成像.
- 使用脑电图 (EEG) 检测神经活动,使用宽带近红外光谱 (bNIRS) 检测新陈代谢速率和含氧血液供应.
- 检查了社交和非社交处理任务期间的大脑反应.
主要成果:
- 在婴儿的社会处理过程中,在 - 关节内显示出空间和时间特定的合激活的增加.
- 在非社会处理过程中观察到同一地区的合激活减少,表明社会特异性.
- 发现社会处理和高频大脑活动 (β和gamma波段) 之间的合最强.
结论:
- 同时的多模式神经成像为婴儿大脑功能专业化提供了新的见解.
- - 关节显示了社会处理的早期专业化,由协调的神经和血液动力学反应支持.
- 高频大脑活动与婴儿在特殊认知功能期间更大的能量需求和局部行动有关.
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