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相关概念视频

Bone Disorders01:29

Bone Disorders

3.6K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
3.6K
Stress-Strain Diagram - Brittle Materials01:24

Stress-Strain Diagram - Brittle Materials

2.5K
Brittle materials, including glass, cast iron, and stone, exhibit unique characteristics. They fracture without considerable change in their elongation rate, indicating that their breaking and ultimate strength are equivalent. Such materials also show lower strain levels at the point of rupture. The failure in brittle materials predominantly results from normal stresses, as evidenced by the rupture created along a surface perpendicular to the applied load. These materials do not display...
2.5K
What is the Skeletal System?01:02

What is the Skeletal System?

52.9K
Overview
52.9K
Fractures: Bone Repair01:27

Fractures: Bone Repair

3.3K
Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the...
3.3K
Spongy Bone01:09

Spongy Bone

4.5K
All bones comprise an outer layer of compact bone, and an interior made up of spongy bone tissue, also called cancellous or trabecular bone. In long bones, spongy bone tissue is mainly found in the interior of the epiphyses (broad ends of the bone).
Spongy bone is more porous, and less dense compared to compact bone. It is composed of concentric lamellae that are arranged irregularly to form the trabecular network. In some bones, the spaces between trabeculae contain red marrow, where...
4.5K
Classification of Bones01:18

Classification of Bones

5.6K
The bones of the human skeletal system are of varied shapes, sizes, and functions. They can be classified based on their shape and function into four major classes: long bones, short bones, flat bones, and irregular bones. Some classifications include a fifth type, the sesamoid bones, as a separate class, whereas others categorize them under short bones.
Long and Short Bones
The appendicular skeleton, particularly the upper and lower limbs, is primarily made of long and short bones. The...
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相关实验视频

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Fragility Assessment of Bovine Cortical Bone Using Scratch Tests
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Fragility Assessment of Bovine Cortical Bone Using Scratch Tests

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[脆弱的骨头]

Mathilde Fargeat1, Fanny Blondet2, Georgios E Papadakis3

  • 1Service de médecine interne générale, Hôpitaux universitaires de Genève, 1211 Genève 14.

Revue medicale suisse
|October 11, 2023
PubMed
概括
此摘要是机器生成的。

长期使用皮质类固醇,特别是超过7.5毫克/天的普得尼松3个月以上,可能导致骨质疏松症和脊椎骨折. 早期骨折风险评估对于预防至关重要.

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Author Spotlight: Enhancing Accuracy and Reproducibility in Whole Bone Bending Tests
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Author Spotlight: An Economic and Efficient Method for Quantitative Evaluation of Bone Microarchitecture in a Murine Osteoporosis Model
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相关实验视频

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科学领域:

  • 内分泌学 在内分泌学.
  • 类风湿病学 类风湿病学
  • 老年病的医生 老年病的医生

背景情况:

  • 皮质类固醇在临床实践中被广泛使用.
  • 长期使用需要考虑骨质疏松症等副作用.
  • 骨质疏松症的风险增加与前尼松剂量>7.5毫克/天>3个月.

研究的目的:

  • 为了强调皮质类固醇诱导的骨质疏松症的风险.
  • 强调在接受皮质类固醇治疗的患者中骨折风险评估的重要性.
  • 倡导预防措施和预防性治疗.

主要方法:

  • 一个69岁的女性患者的病例报告.
  • 关于使用皮质类固醇的临床实践的审查.
  • 二次脊椎压缩骨折的分析.

主要成果:

  • 该患者由于长期治疗腰部疼痛的皮质类固醇而出现了脊椎压缩骨折.
  • 这一案例证明了皮质类固醇治疗的严重并发症.

结论:

  • 在皮质类固醇治疗前和治疗期间评估骨折风险至关重要.
  • 在高危人群中,应考虑预防性治疗.
  • 预防措施可以减轻皮质类固醇诱导的骨损失的不可逆转后果.