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Updated: Jul 13, 2025

Preparation of Stable Bicyclic Aziridinium Ions and Their Ring-Opening for the Synthesis of Azaheterocycles
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Preparation of Stable Bicyclic Aziridinium Ions and Their Ring-Opening for the Synthesis of Azaheterocycles

Published on: August 22, 2018

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1-阿萨斯皮罗 [3.3] 赫作为皮皮瑞丁的生物基

Alexander A Kirichok1,2, Hennadii Tkachuk1, Yevhenii Kozyriev1,3

  • 1Enamine Ltd, Winston Churchill Str. 78, 02094, Kyiv, Ukraine.

Angewandte Chemie (International ed. in English)
|October 11, 2023
PubMed
概括

研究人员合成了1-azaspiro[3.3]heptanes作为piperidine的新型生物异构体. 这些化合物,当纳入布皮瓦卡因时,产生了一个强大的,无专利的麻醉类似物.

关键词:
1-阿萨斯皮罗 (Azaspiro) [3.3] 希普坦 (Heptane) 是一种一种生物异构体 生物异构体药物设计 药物设计药用化学 医学化学皮佩里丁 (Piperidine) 是一种素.

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