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Updated: Jun 14, 2026

In vitro Synthesis of Native, Fibrous Long Spacing and Segmental Long Spacing Collagen

In vitro Synthesis of Native, Fibrous Long Spacing and Segmental Long Spacing Collagen

Published on: September 20, 2012

三种原体支架的特性与本地连接组织相比:一个体外研究

Alex Solderer¹, Nicole Widmer², Andrea Gubler²

¹Division for Periodontology and Peri-Implant Diseases, Clinic of Conservative and Preventive Dentistry, Center of Dental Medicine, University of Zurich, Plattenstrasse 11, 8032, Zurich, Switzerland. alex.solderer@zzm.uzh.ch.

International journal of implant dentistry

|October 11, 2023

概括

原支架 (CS) 呈现出各种吸收,胀和机械性能. 材料组成和微观结构影响它们在模拟生理环境中的性能,影响临床应用结果.

科学领域:

生物材料科学生物材料科学
组织工程是组织工程.
材料科学材料科学材料科学

背景情况:

原体支架 (CS) 在再生医学中使用.
了解它们在生理环境中的行为对于临床成功至关重要.

研究的目的:

为了评估体外再吸收,表面结构,胀和原支架的机械特性.
在模拟生理环境中,将这些特性与猪本地结合组织进行比较.

主要方法:

在人工唾液 (AS) 和模拟体液 (SBF) 中使用高精度秤评估与/或没有原酶的吸收.
通过扫描电子显微镜 (SEM) 分析的表面结构.
在酸盐缓冲盐水 (PBS) 中测量的胀行为和液体吸收.
在PBS中使用循环压缩测试评估的机械性能.

主要成果:

原酶溶液显著增加了再吸收率 (24小时内54.1100%).
SEM显示了交联结构;p-CM和p-ADM显示了与a-ADM不同的状表面.
胀比率和液体吸收遵循这样的模式:p-CM> a-ADM> p-ADM.
p-CM具有更高的弹性; a-ADM和p-CTG的压缩能力较差,在压力下失去完整性.

结论:

原体支架在吸收,胀和机械特性方面表现出显著的变化,这些变化取决于微观结构和组成.
这些特定于材料的差异是实现所需临床结果的关键考虑因素.

关键词:

无细胞皮肤基质.人造唾液的人造唾液这是一个原基质矩阵.结合组织移植结合组织移植吸收率是指吸收率的使用率.扫描电子显微镜 (SEM) 是一种扫描电子显微镜.模拟的体液体液体模拟

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