软组织肉瘤的性别差异:发生率,临床病理学概况,存活率和成本
Alessandra Buja1, Massimo Rugge2,3, Saveria Tropea4
1Laboratory of Healthcare Services and Health Promotion Evaluation, Hygiene and Public Health Unit, Department of Cardiac, Thoracic and Vascular Sciences, and Public Health, University of Padua, Padua, Italy.
Journal of women's health (2002)
|October 11, 2023
概括
男性软组织肉瘤 (STS) 发病率较高且不断上升,可能是由于职业暴露. 性别没有影响STS生存率或临床病理特征. 两性之间的医疗保健费用也相似.
科学领域:
- 在瘤学瘤学.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 在癌症发病率和死亡率上存在基于性别的差异.
- 软组织瘤 (STSs) 是一种罕见的成人恶性瘤,占所有瘤的<1%.
研究的目的:
- 综合分析STS流行病学中的性别差异,包括发病率,临床病理特征,死亡率和医疗保健成本.
- 通过性别分层识别随着时间的推移STS发病率的趋势.
主要方法:
- 基于人口的回顾性研究,使用意大利威尼托地区癌症注册数据 (1990-2018).
- 联合点回归用于发病率趋势分析.
- 对临床病理学和死亡率差异的双变和生存分析.
- 诊断后2年内直接医疗保健支出的成本分析.
主要成果:
- 在研究期间,男性的整体STS发病率较高,在研究期间仅在男性中观察到轻微的上升趋势.
- 短期死亡率或大多数临床病理学资料中没有显著的性别差异,癌症部位分布的变化被注意到.
- 在STS诊断后两年内,直接医疗费用在性别之间没有显著差异.
结论:
- 在STS发病率中男性占主导地位可能与职业暴露于环境变异原体有关.
- 性别不是STS存活率或其临床病理特征的决定因素.
- 与STS相关的医疗保健费用不受患者性别的影响.
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