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Updated: Jul 13, 2025

Modeling Astrocytoma Pathogenesis In Vitro and In Vivo Using Cortical Astrocytes or Neural Stem Cells from Conditional, Genetically Engineered Mice
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Modeling Astrocytoma Pathogenesis In Vitro and In Vivo Using Cortical Astrocytes or Neural Stem Cells from Conditional, Genetically Engineered Mice

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神经瘤学中的临床前质瘤模型:增强翻译研究

Serena Barachini1, Mariangela Morelli2, Orazio Santo Santonocito3

  • 1Department of Clinical and Experimental Medicine, University of Pisa.

Current opinion in oncology
|October 11, 2023
PubMed
概括

由于缺乏合适的临床前模型,开发有效的脑瘤治疗具有挑战性. 本综述探讨了各种模型,以推进神经瘤学研究,并改善患者质瘤的治疗结果.

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Transposon Mediated Integration of Plasmid DNA into the Subventricular Zone of Neonatal Mice to Generate Novel Models of Glioblastoma

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相关概念视频

Mouse Models of Cancer Study02:43

Mouse Models of Cancer Study

Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
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