塞尔维斯特QRS评分是心力衰竭死亡率的预测器,其中保留了喷射分数
Fatih Sivri1, Yahya Kemal Icen2, Hasan Koca2
1Nazilli State Hospital - Department of Cardiology, Aydin - Turquia.
Arquivos brasileiros de cardiologia
|October 11, 2023
概括
塞尔维斯特QRS (S-QRS) 评分预测了心力衰竭患者的长期死亡率,其中包括保留喷射小部分 (HFpEF) 患者. 较高的S-QRS得分表明死亡风险增加,建议将其用作预后指标.
科学领域:
- 心脏病学 心脏病学
- 医学诊断 医学诊断 医学诊断
背景情况:
- 塞尔维斯特QRS (S-QRS) 评分来自12导电心电图 (ECG),与心肌梗塞患者的心肌痕负担和不良预后相关.
- 它在心力衰竭的预后效用与保存的喷射分数 (HFpEF) 仍然未确立.
研究的目的:
- 评估S-QRS得分对诊断为HFpEF的患者死亡风险的预测值.
主要方法:
- 一项涉及359名HFpEF患者的回顾性研究.
- 收集了心电图,心声图和实验室数据,包括简化的S-QRS得分.
- 随访持续时间平均为38.1±9.5个月.
主要成果:
- 与幸存者 (270名患者) 相比,死亡组 (89名患者) 的年龄,Hs-CRP,热素,亲BNP,左心房 (LA) 直径,LA体积指数,QRS持续时间,Tpe和S-QRS得分较高.
- 多变量分析确定了年龄,Hs-CRP,NT-proBNP,LA直径,LA体积指数,Tpe和S-QRS得分作为独立的死亡风险因素.
- 接收器运行特征 (ROC) 分析表明S-QRS得分切线为5.5 (AUC:0.880,灵敏度:80.8%,特异性:77.2%). 卡普兰-梅尔分析证实,S-QRS得分≥5.5 (p<0.001) 的死亡率更高.
结论:
- 在HFpEF患者中,S-QRS得分显示出作为长期死亡率的预后生物标志物的显著潜力.
- 建议将其应用于HFpEF管理中的随时可用的预测工具.
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