通过超音速剪切波成像来诊断皮皮质弹性的诊断性能,用于儿科膜病的儿科膜病
Li-Qiong Shi1, Jie Sun1, Li Yuan1
1Department of Ultrasound Imaging, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science & Technology, No. 100 Xianggang Road, Wuhan City, Hubei 430016, China.
European journal of radiology
|October 11, 2023
概括
超音速剪切波成像 (SSI) 通过测量皮层弹性 (Young) 来有效诊断儿科球性疾病.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 生物医学工程 生物医学工程
- 医疗成像医学成像
背景情况:
- 儿科球体疾病的诊断通常依赖于诸如活检之类的侵入性方法.
- 需要非侵入性成像技术来评估儿童的脏健康状况.
- 皮层弹性可能表明疾病的进展和严重程度.
研究的目的:
- 用超音速剪切波成像 (SSI) 评估皮皮质弹性的诊断准确性,用于儿科球性疾病.
- 确定皮质的模量 (YM) 作为诊断标记.
- 为了比较患有淋巴细胞疾病的儿童和健康对照组之间的YM值.
主要方法:
- 包括71名经活检确认患有淋巴细胞疾病的儿童和60名健康志愿者.
- 传统和SSI超声波检查均对两进行.
- 测量了脏皮层的脏尺寸,阻力指数 (RI) 和YM.
主要成果:
- 与对照组相比,YM在淋巴细胞疾病组显著更高 (P < 0.001).
- 左脏中极的YM显示了最高的诊断性能 (AUC = 0.936),截止值为15.48kPa (灵敏度为87.3%,特异性为86.7%).
- 在不同病理类型或等级的淋巴细胞疾病中,没有发现YM的显著差异,也没有与大多数临床和实验室参数有显著的相关性.
结论:
- 超声波切割波成像 (SSI) 是一种可行的,非侵入性的方法来诊断儿科质细胞疾病.
- 通过SSI测量皮层弹性显示出作为诊断工具的潜力.
- 在这个儿科队列中,SSI没有有效地区分各种病理亚型或疾病严重程度等级.
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