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Updated: Jul 30, 2026

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对RACK1的物种特异性FMRP调节对于产前皮质发育至关重要

Minjie Shen1, Carissa L Sirois1, Yu Guo1

  • 1Waisman Center, University of Wisconsin-Madison, Madison, WI 53705, USA; Department of Neuroscience, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53705, USA.

Neuron
|October 11, 2023
PubMed
概括

脆弱的X信使核糖蛋白1蛋白 (FMRP) 缺乏会损害产前大脑发育,导致线粒体问题和过度兴奋. 增强线粒体功能可以治疗脆弱X综合征 (FXS).

关键词:
FMR1 FMR1 的使用情况.FMRP 交互器的交互器在RACK1中,使用RACK1.外生皮层切片的外生皮层切片脆弱的X综合征 脆弱的X综合征人类的特异性生理学马可克 (Macaque) 是一个巨.线粒体中的线粒体.多元干细胞是多元的干细胞.

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Epistasis01:39

Epistasis

In addition to multiple alleles at the same locus influencing traits, numerous genes or alleles at different locations may interact and influence phenotypes in a phenomenon called epistasis. For example, rabbit fur can be black or brown depending on whether the animal is homozygous dominant or heterozygous at a TYRP1 locus. However, if the rabbit is also homozygous recessive at a locus on the tyrosinase gene (TYR), it will have an unshaded coat that appears white, regardless of its TYRP1...