跨性别者的心血管疾病
Charlotte N Murphy1, Christian Delles1, Eleanor Davies1
1School of Cardiovascular and Metabolic Health, University of Glasgow, United Kingdom.
Atherosclerosis
|October 11, 2023
概括
性别确认激素治疗 (GAHT) 可能会增加心血管疾病的风险. 需要更多的研究来了解 GAHT 的机制,并为经历 GAHT 的跨性别个体指导医疗保健.
科学领域:
- 内分泌学 在内分泌学.
- 心血管医学 心血管医学
- 公共卫生 公共卫生
背景情况:
- 越来越多的跨性别人口寻求性别确认医疗保健 (GAHT).
- GAHT提供了诸如改善性别障碍症和心理社会功能等好处.
- 新出现的证据表明GAHT可能会增加心血管疾病 (CVD) 风险.
研究的目的:
- 研究跨性别者的心血管健康状况.
- 了解将GAHT与心血管疾病风险联系在一起的机制.
- 解决转女性性GAHT和心血管疾病的研究缺口.
主要方法:
- 审查关于GAHT和心血管结果的现有文献.
- 对潜在机制的分析,包括荷尔蒙作用和途径参与.
- 考虑跨性别人口中多因素心血管疾病风险.
主要成果:
- 跨男性性GAHT () 可能通过氧化路径,炎症和内皮功能障碍增加心血管疾病风险.
- 对女性转移性GAHT (雌激素) 和心血管疾病风险的研究严重缺乏.
- 心理社会压力因素 (压力,吸烟,歧视,社会经济地位) 也会影响心血管疾病风险.
结论:
- 进一步的研究至关重要,以阐明GAHT在跨性别人群中的心血管影响.
- 了解机制是制定有针对性的医疗保健和指导的关键.
- 解决多因素风险对于全面的心血管护理至关重要.
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