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Updated: Jul 13, 2025

Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay
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作为一种开发细胞毒性分子向癌细胞发展的策略,对自然存在的化合物的结构修饰

Pedro Olim1, Renato B Pereira1, Maria José G Fernandes2

  • 1REQUIMTE/LAQV, Laboratory of Pharmacognosy, Department of Chemistry, Faculty of Pharmacy, University of Porto, Porto, Portugal.

Archiv der Pharmazie
|October 11, 2023
PubMed
概括

两种新型的6-基原衍生物对胃癌和肺癌细胞表现出强有力的和选择性的抗癌活性. 这些化合物在不损害细胞膜完整性的情况下诱导细胞亡,为新的癌症治疗提供了有希望的线索.

关键词:
6 - 基黄 (Hydroxyflavanone) 是一种基黄.癌症 癌症 癌症 癌症 癌症细胞毒性 细胞毒性尤金诺醇是一种蒂莫尔 (thymol) 是一种蛋白质.

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