奥米克斯对饮食的反应的洞察力
Ana Arias-Borrego1,2, Belén Callejón-Leblic1, Maria Carmen Collado3
1Research Center of Natural Resources, Health and the Environment (RENSMA), Department of Chemistry, Faculty of Experimental Sciences, University of Huelva, Fuerzas Armadas Ave., Huelva, Spain.
Proteomics
|October 11, 2023
概括
对健康至关重要,但过量有毒. 奥米克斯的方法揭示了饮食中的如何影响健康,新陈代谢和肠道微生物,指导安全的补充策略.
科学领域:
- 营养生物化学和分子生物学.
- 综合体和系统生物学.
背景情况:
- 是一种重要的微量元素,具有多种健康益处,包括癌症化学预防和神经保护.
- 饮食中的水平需要谨慎管理,因为必需剂量和有毒剂量之间的窗口很窄.
- 缺乏导致了富含食物和补充剂的开发.
研究的目的:
- 审查omics方法的应用,以了解饮食中的代谢和哺乳动物中的生物作用.
- 要突出获得的关于蛋白功能,组织特异性代谢和肠道微生物群相互作用的见解.
主要方法:
- 对包括蛋白质组学,金属组学,代谢组学和元taxonomics在内的omics方法的审查.
- 整合omics数据与基因组学和转录组学,以获得全面的视图.
- 专注于研究中的工作流程和omics的应用.
主要成果:
- 奥米克斯的方法提供了对代谢和生物功能的深入了解.
- 详细了解蛋白的作用,血液和组织代谢 (大脑,生殖器官),以及肠道微生物群的影响.
- 描述对微生物代谢物的影响.
结论:
- 奥米克的方法是阐明饮食的复杂影响的强大工具.
- 通过这些综合方法,可以更深入地了解的生物作用和安全补充策略.
更多相关视频
04:54Assessing Mineral Availability in Fish Feeds using Complementary Methods Demonstrated with the Example of Zinc in Atlantic Salmon
Published on: October 29, 2021
3.1K
09:04DNBS/TNBS Colitis Models: Providing Insights Into Inflammatory Bowel Disease and Effects of Dietary Fat
Published on: February 27, 2014
47.5K
相关概念视频
Sulfur Assimilation
20
Sulfur is an essential element in biological systems, contributing to synthesizing key biomolecules, including amino acids such as cysteine and methionine, and cofactors such as coenzyme A and biotin. Microorganisms primarily assimilate sulfur as sulfate (SO₄²⁻) from the environment, which must undergo a series of biochemical transformations before it can be incorporated into cellular components. As sulfate is highly oxidized, it must undergo assimilatory sulfate reduction to...
20
Responses to Salt Stress
13.2K
Salt stress—which can be triggered by high salt concentrations in a plant’s environment—can significantly affect plant growth and crop production by influencing photosynthesis and the absorption of water and nutrients.
13.2K
Overview of Metabolism
30.5K
Living cells constantly carry out various chemical reactions which are necessary for their proper functioning. These reactions are interlinked to one another via multiple pathways. The collection of these chemical reactions is known as metabolism.
Plant Metabolism
Sunlight, the primary source of energy in plants, is first absorbed by the chlorophyll pigments present in their leaves. Plants then use this energy to carry out photosynthesis, where water is oxidized into oxygen and carbon dioxide...
Plant Metabolism
Sunlight, the primary source of energy in plants, is first absorbed by the chlorophyll pigments present in their leaves. Plants then use this energy to carry out photosynthesis, where water is oxidized into oxygen and carbon dioxide...
30.5K
Dose-Response Relationship: Overview
3.2K
Agonists can bind with and activate receptors, resulting in the formation of drug-receptor complexes. Once formed, these complexes catalyze many biochemical processes at the cellular level and subsequently induce a pharmacologic response. The degree of response is directly proportional to the fraction of activated receptors, which in turn, depends on the concentration of the drug at the receptor site as well as the sensitivity of the receptor. An increase in the administered dose contributes to...
3.2K
