在24小时的门诊血压监测期间高与低测量频率 - 一个随机交叉研究
Martin B Thomsen1,2, Jakob Nyvad1, Kent L Christensen3
1Department of Renal Medicine, Aarhus University Hospital, Aarhus, Denmark.
Journal of human hypertension
|October 11, 2023
概括
低频门诊血压监测 (ABPM) 提供与高频ABPM类似的血压读数,但不那么不舒服. 这种降低频率的ABPM方法为在监测期间经历疼痛的患者提供了可行的替代方案.
科学领域:
- 心脏病学 心脏病学
- 高血压管理 高血压管理
- 临床试验 临床试验
背景情况:
- 门诊血压监测 (ABPM) 对于诊断和管理高血压至关重要.
- 患者的不适和压力,可能与袖口膨胀频率有关,可能会影响ABPM的准确性和坚持.
- 目前的ABPM指南建议使用更高的通胀频率,这可能会增加患者的负担.
研究的目的:
- 在血压读数方面,比较低频ABPM (LF-ABPM) 和高频ABPM (HF-ABPM) 之间的一致性.
- 评估患者报告的与LF-ABPM和HF-ABPM相关的疼痛和睡眠障碍.
- 确定LF-ABPM是否是一种临床上可接受的替代HF-ABPM.
主要方法:
- 采用交叉研究设计,随机分配171名患者接受LF-ABPM (一次膨胀/小时) 和HF-ABPM (白天每小时三次膨胀,夜间两小时).
- 患者使用视觉模拟尺度报告疼痛,并在每个监测期后注意到睡眠障碍.
- 主要终点是两个监测频率之间的平均24小时缩血压 (SBP) 的差异.
主要成果:
- 总共有131名患者完成了这项研究. 平均24小时SBP显示,LF-ABPM (138.2 mmHg) 和HF-ABPM (137.5 mmHg) 之间的良好一致性,平均差异为-0.7 mmHg.
- 对于SBP的变化系数在两个监测频率中都是相似的.
- 与HF-ABPM相比,LF-ABPM在白天和夜间报告的疼痛得分明显较低.
结论:
- LF-ABPM和HF-ABPM提供了可比的血压测量,没有临床上显著的差异.
- 通过减少与手术相关的疼痛和不适,LF-ABPM为接受门诊血压监测的患者提供了一种有价值的替代方案.
- 这些发现支持可能采用LF-ABPM协议,以改善患者在高血压管理中的体验.
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