牙弧形和闭口特征的遗传性:一个系统的审查和元分析
Jamal Giri1, Michelle Bockmann1, Alan Brook1
1Adelaide Dental School, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, SA, Australia.
European journal of orthodontics
|October 11, 2023
概括
这项研究发现,牙弧度的尺寸具有很高的遗传性,而闭塞参数显示中度到低的遗传性. 这些发现澄清了对牙和咬对齐的遗传影响.
科学领域:
- 遗传学 遗传学是一种遗传学.
- 矯正牙科 矯正牙科是一種矯正牙科.
- 人类牙是人类的牙.
背景情况:
- 牙气囊特征的遗传基础是复杂的,发现往往是模两可的.
- 了解遗传性对于诊断和治疗缺陷症至关重要.
- 之前的研究对遗传影响产生了不一致的结果.
研究的目的:
- 系统地审查和进行关于牙弧形和闭口参数遗传性的元分析.
- 综合现有的关于各种牙和面部特征的遗传贡献的证据.
- 为特定的牙和闭口特征提供遗传性的定量估计.
主要方法:
- 经验研究的系统审查和元分析.
- 搜索了多个电子数据库,直到2023年8月.
- 包括双胞胎和兄弟姐妹研究,评估dentoalveolar参数的遗传性.
- 使用既定标准评估偏见风险和证据确定性 (乔安娜·布里格斯研究所,GRADE).
主要成果:
- 包括28项研究,15项适用于永久牙的元分析.
- 发现了大和下弓尺寸 (例如,间宽度,弓长) 和口腔深度的高遗传率估计.
- 对交叉咬伤,超咬伤,超喷射和牙旋转等闭合参数的中低遗传概率估计.
结论:
- 牙弧的尺寸具有很高的遗传性,表明有很强的遗传影响.
- 异位参数显示遗传性中度至低,这表明环境因素的作用更大.
- 对大多数结果的证据确定性被评为低,需要进一步研究.
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