在南非高省的器官分布不平等:挑战和解决方案
Priya Walabh1,2,3, Sechaba T Palweni3,4,5, Christina Hajinicolaou1,6,7
1Department of Paediatrics and Child Health, School of Clinical Medicine, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa.
Pediatric transplantation
|October 12, 2023
概括
在南非高省,器官捐赠的差异仍然存在,不成比例地影响到公共部门和儿科接受者. 需要改进的政策来解决这些不平等的固体器官移植.
科学领域:
- 移植研究 移植研究
- 公共卫生政策 公共卫生政策
- 器官捐赠和分配器官的情况
背景情况:
- 南非在获得器官方面面临重大挑战,特别是在高省,由于社会经济和政治因素影响器官分配.
- 尽管有着先进的器官移植的历史,但公平的获取仍然是一个关键问题.
研究的目的:
- 评估公共部门对高省固体器官移植的贡献.
- 为了比较公共部门和私营部门接收者之间的固体器官分布.
主要方法:
- 来自高州公共部门的同意性脑死亡捐赠者的回顾性注册表审查 (2016年1月 - 2021年6月).
- 数据协调在夏洛特·马克塞克约翰内斯堡学术医院.
- 对49位已故捐赠者的记录进行分析.
主要成果:
- 在心脏 (p=.012) 和肝脏 (p<.001) 移植中,在公共部门和私营部门之间观察到器官分配的显著差异.
- 在所有固体器官 (p<.001) 中,成人与儿科接受者的分配也明显存在差异.
- 2020年3月1日之后,在公共部门授权的等候名单过渡 (p=.0026) 之后,儿科脏移植的显著增加发生了.
结论:
- 目前的器官分配差异显著影响公共部门的接受者,儿童患者尤其容易受到伤害.
- 这些不平等可能源于缺乏立法和资源限制.
- 建议改善政府政策,并明确优先考虑移植单位的儿科患者.
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