下肢动脉疾病的前景:IUA关于"管理"的共识文件. 第1部分 第1部分
Pier Luigi Antignani1, Mauro Gargiulo2, Giacomo Gastaldi3
1Vascular Center, Nuova Villa Claudia, Rome, Italy - antignanipl@gmail.com.
概括
动脉样性心血管疾病 (ASCVD) 带来重大风险,特别是在糖尿病患者 (DM) 身上. 本文档涉及ASCVD流行病学,风险因素,预防和治疗,重点关注下肢动脉疾病 (LEAD).
科学领域:
- 血管医学和血管学
- 心脏病学 心脏病学
- 糖尿病学 糖尿病学
背景情况:
- 动脉样性心血管疾病 (ASCVD),包括冠心病 (CHD),脑血管疾病和下肢动脉疾病 (LEAD) /周围动脉疾病 (PAD),是全球主要的健康问题.
- ASCVD是致病率和死亡率的主要原因,特别是在糖尿病患者中.
- 国际血管病学联盟召开会议,以解决ASCVD的多方面的问题.
研究的目的:
- 为ASCVD的流行病学和风险因素提供全面的共识.
- 概述ASCVD的初级和二级预防策略.
- 阐明糖尿病和LEAD/PAD之间的具体相关性,并讨论当前的治疗方式.
主要方法:
- 对ASCVD流行和发病率的流行病学数据的审查.
- 对ASCVD发展和进展的既定和新兴风险因素的分析.
- 目前关于糖尿病患者LEAD/PAD保守和手术治疗选择的证据综合.
主要成果:
- ASCVD仍然是导致死亡的主要原因,而DM显著加剧了风险和严重程度,特别是在LEAD/PAD.
- 有效的风险因素管理和有针对性的预防对于减少ASCVD负担至关重要.
- 结合医疗管理和再血管化策略的综合方法对于在糖尿病患者中治疗LEAD/PAD至关重要.
结论:
- ASCVD,特别是当与DM相关时,需要一个多学科的方法来有效管理.
- 早期检测,风险因素修改和及时干预是改善ASCVD和DM患者治疗结果的关键.
- 对DM与LEAD/PAD之间的特定病理生理联系的进一步研究可能会产生新的治疗目标.
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