来自活体供体高BMI肝移植的实践模式和考虑因素:一篇综述
Carl Samaha1, Hadi Chaaban1, Cem Simsek1
1Division of Gastroenterology and Hepatology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Hepatology forum
|October 12, 2023
概括
肥胖的捐赠者可以有资格接受活体捐赠者肝移植 (LDLT),但需要标准化标准和优化. 本综述审查了全球实践,捐赠者选择,以及LDLT中肥胖捐赠者的结果.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 移植手术 移植手术
- 公共卫生 公共卫生
背景情况:
- 活体供体肝移植 (LDLT) 解决了对末期肝病的供体器官短缺问题.
- 潜在的活体肝脏捐赠者的肥胖症带来了挑战和关于资格的持续辩论.
- 身体质量指数 (BMI) 分布的全球变化需要量身定制的供体选择标准.
研究的目的:
- 审查有关肥胖捐赠者的LDLT的全球实践和看法.
- 确定当前的捐赠者资格标准,并讨论对肥胖个体的特殊考虑.
- 检查使用LDLT中肥胖捐赠者的结果和并发症.
主要方法:
- 对LDLT的全球实践进行了全面的文献综述.
- 对捐赠者资格标准的分析,包括BMI和人口特异性因素.
- 对报告肥胖捐赠者的LDLT结果和并发症的研究的评估.
主要成果:
- 对于肥胖个体的捐赠者选择标准存在显著的全球差异.
- 对于精选的肥胖捐赠者来说,非侵入性检测和术前优化肝硬化症至关重要.
- 涉及肥胖捐赠者的LDLT的结果和并发症需要进一步调查和标准化.
结论:
- 在LDLT中选择肥胖的捐赠者需要标准化指南.
- 对肥胖捐赠者的非侵入性评估和优化策略进行进一步的研究是必不可少的.
- 包括精心挑选的肥胖捐赠者可能会扩大LDLT的捐赠池.
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