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Updated: Jul 13, 2025

On-Chip Endothelial Inflammatory Phenotyping
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系统性炎症中的内皮屏障功能障碍是由可溶性VE-cadherin介导的,它干扰VE-PTP信号传输

Juna-Lisa Knop1, Natalie Burkard1, Mahshid Danesh2

  • 1Department of General, Visceral, Transplantation, Vascular and Paediatric Surgery (Department of Surgery I), University Hospital Wuerzburg, Oberduerrbacherstraße 6, D-97080 Wuerzburg, Germany.

iScience
|October 12, 2023
PubMed
概括

可溶性血管内皮质 (VE) - 阴素碎片 (sVE- 阴素) 直接导致内皮质屏障功能障碍,这是与败血症相关的器官损伤的关键因素. 准VE-PTP/RhoA信号可能为败血症提供新的治疗策略.

关键词:
生物科学 生物科学细胞生物学 细胞生物学分子生物学分子生物学

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