一个关于酸作为抗菌和抗癌剂的潜在机制的更新
Saeedeh Keyvani-Ghamsari1, Maryam Rahimi1, Khatereh Khorsandi2
1Clinical Cares and Health Promotion Research Center, Karaj Branch Islamic Azad University Karaj Iran.
Food science & nutrition
|October 12, 2023
概括
酸 (GA) 是一种天然的多,通过破坏细菌生长和抑制癌细胞增殖,显示出显著的抗菌和抗癌特性. 这篇评论探讨了GA的GA.
科学领域:
- 药理学和天然产品化学
- 抗微生物和抗癌研究
背景情况:
- 对抗菌和抗癌药物的耐药性是全球卫生面临的关键挑战.
- 自然化合物提供了一个有前途的替代品,因为它们的疗效和最小的副作用.
- 酸 (GA),一种植物多,表现出各种健康促进性质.
研究的目的:
- 审查关于酸 (GA) 的来源,化学性质和药理学方面的最新发现.
- 综合分析GA及其衍生物的抗菌和抗癌活性.
- 探索GA在药物组合和纳米配方中的潜力,以提高治疗结果.
主要方法:
- 关于酸 (GA) 的现有研究的文献综述.
- 对GA对细菌和癌细胞的作用机制的分析.
- 在单一治疗,联合治疗和纳米配方中评估GA的疗效.
主要成果:
- 酸 (GA) 通过膜改变,代谢干扰和生物膜抑制来抑制细菌的生长.
- 通过向细胞灭绝,细胞循环,ROS生产和瘤基因,GA抑制癌细胞增殖.
- GA及其衍生物在组合疗法和纳米配方中显示出潜力.
结论:
- 酸 (GA) 具有强大的抗菌和抗癌特性,解决了关键的全球健康问题.
- 为了扩大临床应用,需要对GA及其衍生物,包括纳米配方进行进一步的研究.
- 本综述为在未来的治疗策略中利用 GA 提供了一个全面的视角.
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