支持人类"动脉"静脉回流机制的证据
Jeremy N Cohen1, Rose A Samra1, Jason S Au1
1Department of Kinesiology and Health Sciences, University of Waterloo, Waterloo, Ontario, Canada.
Journal of applied physiology (Bethesda, Md. : 1985)
|October 12, 2023
概括
动脉机制,邻近的动脉协助附近的静脉,有助于在改变身体位置时保持血液流动. 这项研究提供了体内证据,证明这种效应可以保持静脉回归,这表明它.
科学领域:
- 心血管生理学心血管生理学
- 血液动力学 血液动力学
- 静脉回归机制 静脉回归机制
背景情况:
- 对于静脉回流的传统理解强调肌肉和呼吸道.
- 最近的ex vivo研究表明,静脉动脉捆中的新型动脉效应.
- 脉动性动脉能量向相邻静脉的传输在体内并未得到充分理解.
研究的目的:
- 在人体中研究动脉机制的体内证据.
- 评估水静压变化对捆绑和非捆绑静脉静脉血流的影响.
- 为了确定相邻的动脉是否在增加的静脉压力梯度期间保护静脉流动.
主要方法:
- 在16名健康成年人中测量了深股骨静脉 (DFV,捆绑) 和大静脉 (GSV,非捆绑) 的静脉血流.
- 使用随机的身体位置: -6°向下倾斜 (HDT),仰卧,20°向上倾斜 (HUT) 和40°向下倾斜.
- 评估了不同水静压下静脉血流和静脉直径的变化.
主要成果:
- 捆绑的DFV血流在20°和40°HUT之间保持稳定 (68 ± 36对比71 ± 56毫升·分钟-1).
- 非捆绑的GSV血流在20°和40°HUT之间显著下降 (6.1±4.8对3.5±3.9毫升·分钟-1).
- 使用HUT,DFV直径显著增加,而GSV直径没有变化.
结论:
- 在体内数据支持存在动脉机制,保护静脉回归.
- 邻近动脉的存在保护捆绑静脉在增加的水静压下减少流量.
- 动脉是静脉回归的一个被低估的贡献者,需要进一步研究.
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