量化野生子对myxomatosis的耐药性产生了新的进化见解
Brian D Cooke1, Patrick Taggart2,3,4, Kandarp Patel2
1Institute for Applied Ecology, University of Canberra, Bruce, Australian Capital Territory, Australia.
Epidemiology and infection
|October 12, 2023
概括
澳大利亚野生子对菌瘤病毒 (MV) 产生了快速的遗传抵抗力. 这种进化变化随着子跳的引入而加速,突出显示了对子种群的持续监测的需要.
科学领域:
- 进化生物学是进化的生物学.
- 兽医科学是一门兽医科学.
- 生态生态学 生态生态学
背景情况:
- 菌瘤病毒 (MV) 引入澳大利亚用于对侵入性子进行生物控制.
- 子种群已经表现出对MV的遗传耐药性,但这种进化的速度尚不清楚.
- 侵入性子在全球范围内构成重大经济和环境威胁.
研究的目的:
- 评估澳大利亚野对菌瘤病毒的遗传耐药性发展速度.
- 分析欧洲子跳作为载体对抗药性演变的影响.
- 建议继续监测子对myxoma病毒的耐药性.
主要方法:
- 从澳大利亚的挑战试验中收集的数据,估计了子对菌病的抵抗力.
- 在连续规模上表达了阻力,以评估45年 (至1995年) 的趋势.
- 澳大利亚与英国的抗药性发展比较.
主要成果:
- 子对菌病的耐药性最初迅速增加,随后长达十年的平原.
- 耐药性的第二次快速增长恰逢欧洲子的引入.
- 在英国,跳已经存在,但耐药性发展得更慢.
- 近30年来,尽管出现了新的子病原体,但没有对耐药性的估计.
结论:
- 子跳载体显著影响了瘤病毒耐药性演变的速度.
- 建议在澳大利亚继续对野生子进行测试,以评估当前的myxomatosis有效性.
- 由于它们的经济和环境影响,对侵入性子的有效管理至关重要.
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