针对结肠提供多醇:构建原理,向机制和评估方法
Yidi Wang1, Zhiying Li1, Yiwen Bao1
1College of Food Science, Shenyang Agricultural University, Shenyang, Liaoning, China.
Critical reviews in food science and nutrition
|October 12, 2023
概括
多提供结肠健康益处,但在肠道中降解. 开发针对结肠的输送系统可以提高多的稳定性,向性和生物可用性,从而改善治疗结果.
科学领域:
- 药理学 药理学是指药理学的学科.
- 胃肠病学 胃肠病学
- 药物输送系统 药物输送系统
背景情况:
- 多因其对结肠健康的有益影响而得到认可.
- 聚醇容易在胃肠道中降解,需要采取保护措施.
- 有效的输送系统对于增强多稳定性,结肠向性和生物可用性至关重要.
研究的目的:
- 审查对聚醇的结肠向控制释放系统的研究.
- 讨论影响多醇在结肠中的输送和吸收的生理因素.
- 总结各种结肠向的载体,它们的释放机制和评估模型.
主要方法:
- 讨论影响大肠中多溶解,释放和吸收的生理因素.
- 描述不同类型的结肠向性载体及其释放机制.
- 对现有的结肠向性评估模型的摘要和批判性分析.
主要成果:
- 确定影响结肠中多输送系统的关键生理特征.
- 根据它们的释放策略对结肠向的载体进行分类.
- 评估当前结肠向评估方法的优缺点.
结论:
- 针对结肠的输送系统对于最大限度地发挥多的治疗潜力至关重要.
- 需要对先进运营商和评估模型进行进一步的研究.
- 针对结肠的新型治疗方法的战略开发可以确保多在结肠中的生物活性.
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