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During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
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Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
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Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
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相关实验视频

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选择性手术后成功的衰老II:研究队列描述研究队列描述

Michelle Ward1, Tammy T Hshieh2,3,4, Eva M Schmitt2

  • 1Division of General Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.

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概括

在SAGES II研究中,招募了420名接受手术的老年人,收集了认知健康和生物标志物的数据. 这项研究为了解手术后妄想症和痴呆症风险提供了基础.

关键词:
生物标志物 生物标志物认知能力下降 认知能力下降认知障碍是一种认知障碍.妄想 妄想 妄想 妄想 妄想痴呆症 痴呆症是一种痴呆症.长期的认知能力下降.

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科学领域:

  • 老年学是指老年学的学科.
  • 神经科学是一个神经科学.
  • 外科手术的结果

背景情况:

  • 选择性手术后成功衰老 (SAGES) II研究调查了痴呆症和阿尔茨海默病以及相关痴呆症 (AD/ADRD) 之间的联系.
  • 该研究捕捉了在接受手术的老年人中新的液体生物标志物,神经成像和神经生理学测量.
  • 了解这些关系对于改善老年人群认知健康结果至关重要.

研究的目的:

  • 提供SAGES II队列的全面描述,包括基线特征和数据完成率.
  • 详细说明由于COVID-19大流行,对研究协议进行的修改.
  • 为未来利用SAGES II队列的研究奠定基础.

主要方法:

  • 一项前性观察队列研究,涉及65岁及以上的社区居民接受重大非心脏手术的成年人.
  • 参与者在手术前,住院期间以及出院后的1,2,6,12和18个月被评估.
  • 实施了包括视频评估在内的修改程序,以保持COVID-19大流行期间的数据质量.

主要成果:

  • 约有420名参与者被录取,平均年龄为73.4岁;14%来自少数民族背景.
  • 88%的参与者接受了全膝盖或关节置换手术.
  • 尽管面临流行病的挑战,但数据完成率很高,近90%的访谈完成了长达6个月的随访.

结论:

  • 这项SAGES II研究是独一无二的,因为它专注于使用新生物标志物的手术结果和妄的危险因素.
  • 本文介绍了SAGES II队列及其收集的数据的首次描述.
  • 这项研究为未来关于衰老,手术和认知衰退的研究提供了宝贵的资源.