肝细胞癌中明显改变的脂质成分与受损的T细胞依赖性抗瘤免疫有关

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Xue Cheng1, Wei Wang1, Ziyao Zhang1

  • 1Department of Immunology, School of Basic Medicine, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Disease, Huazhong University of Science and Technology, Wuhan, 430030, China.

Hepatology international
|October 12, 2023
PubMed
概括

与乙型肝炎病毒相关的肝癌中脂肪代谢的改变会损害T细胞的抗瘤免疫力. 减少长链乙卡尼丁 (LCACs) 和增加 lysophosphatidylcholines (LPCs) 可能会增强用于免疫治疗的T细胞功能.

关键词:
抗瘤免疫力 抗瘤免疫力有缺陷的功能功能.肝细胞癌是肝细胞癌.IFN-γ 的分泌物脂质代谢 脂质代谢 是一种长链乙卡尼丁是什么Lysophosphatidylcholines 溶解胺基胆的含量是多少T细胞耗尽的情况瘤代谢微环境中的微环境瘤透的T细胞已经进入了瘤.

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