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Updated: Jul 13, 2025

Author Spotlight: Integrated Multi-Omics Analysis for Unveiling Multicellular Immune Signatures in Clinical Heart Attack Cohorts
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Published on: September 20, 2024

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通过整合性多组全方位关联研究获得了对缺血性中风病因学的新见解

Junghyun Jung1, Zeyun Lu2, Adam de Smith1

  • 1Center for Genetic Epidemiology, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, 1450 Biggy Street, Los Angeles, CA 90033, United States.

Human molecular genetics
|October 12, 2023
PubMed
概括

这项研究通过整合大规模的基因组和分子数据,确定了136个基因,增强器RNA和与缺血性中风 (IS) 风险相关的蛋白质. 它还建议脱氧胆酸作为IS的潜在治疗剂.

关键词:
药物重新定位 药物重新定位缺血性中风 中风多个组的全组关联研究.全现象关联研究和遗传相关性分析.

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