相关实验视频

Updated: Jul 13, 2025

Routine Screening Method for Microparticles in Platelet Transfusions

Routine Screening Method for Microparticles in Platelet Transfusions

Published on: January 31, 2018

在重症监护中减少输血的小体积血液采集管:STRATUS随机临床试验

Deborah M Siegal^1,2,3,4, Emilie P Belley-Côté^1,2,5, Shun Fu Lee^1,5

¹Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada.

|October 12, 2023

概括

在重症监护室 (ICU) 转换为小体积血液采集管可能会减少红细胞 (RBC) 输血,但不会影响实验室测试的准确性. 这种变化有助于缓解危急病患者的贫血.

科学领域:

危急护理医学
血液学
实验室科学

背景情况:

在重症监护室 (ICU) 采集血液有助于贫血和红细胞输血.
收集的大量血液往往被丢弃, 因为它超过了分析要求.

研究的目的:

评估是否转换为小体积血液采集管在ICU减少红细胞输血.
评估这种过渡是否会影响实验室测试程序.

主要方法:

在加拿大25个成年医疗外科重症监护室进行了一项阶梯集随机试验.
从标准体积到小体积真空管进行血液采集.
主要结局是每位患者每次ICU住院的红细胞输血单位;次要结局包括输血率,血红蛋白变化和样本充分性.

主要成果:

在初级分析中 (21, 201名患者),没有观察到每位患者每次ICU住院的红血细胞单位有显著差异 (RR, 0. 91; P=19).
一个预先规定的二次分析 (27,411名患者) 显示每位患者每次ICU住院的红细胞单位显著下降 (RR,0. 88;P=. 04).
样本体积不足以进行分析是罕见的 (≤0.03%),在初级分析中,输血调整后的血红蛋白变化没有显著差异.

结论:

在重症监护室使用小容量的血液采集管有可能减少红细胞输血.
这种做法似乎保持了实验室检测程序的完整性.
这些发现表明可以修改的策略,以减少危急病患者的阳性贫血和输血需求.

更多相关视频

A Clinical Trial Assessing the Safety, Efficacy, and Delivery of Olive-Oil-Based Three-Chamber Bags for Parenteral Nutrition

A Clinical Trial Assessing the Safety, Efficacy, and Delivery of Olive-Oil-Based Three-Chamber Bags for Parenteral Nutrition

Published on: September 20, 2019

Preparation of Peripheral Blood Mononuclear Cell Pellets and Plasma from a Single Blood Draw at Clinical Trial Sites for Biomarker Analysis

Preparation of Peripheral Blood Mononuclear Cell Pellets and Plasma from a Single Blood Draw at Clinical Trial Sites for Biomarker Analysis

Published on: March 20, 2021

相关概念视频

Blood Transfusion and Agglutination

Blood Transfusion and Agglutination

Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...