红细胞输血:2023年AABB国际指南
Jeffrey L Carson1, Simon J Stanworth2,3,4,5, Gordon Guyatt6
1Department of Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey.
JAMA
|October 12, 2023
概括
对于大多数住院的成年人和重症儿童,建议限制红细胞输血策略. 这些方法使用较低的血红蛋白值,对患者的结果没有不利影响,被认为是良好的做法.
科学领域:
- 血液学
- 输血医学
- 临床指南
背景情况:
- 红细胞输血是一种常见的医疗干预,
- 确定最佳的输血门对于患者的安全和有效护理至关重要.
研究的目的:
- 为成人和儿童提供基于证据的红细胞输血建议.
- 为临床医生提供适当的血红蛋白值指导.
主要方法:
- 对随机对照试验 (RCT) 进行了系统审查.
- 使用推评估,开发和评价 (GRADE) 方法.
- 利益冲突得到了管理,价值观和偏好得到了明确.
主要成果:
- 对于大多数成人和儿童患者来说,限制性输血值 (血红蛋白< 7 g/ dL) 并没有对结果产生不良影响.
- 对稳定的住院成年人和重病儿童提出严格的建议.
- 对患有血液病/ 瘤病和特定儿科心脏病的成年人提出了限制性策略的条件建议.
结论:
- 在各种患者群体中,限制性红细胞输血策略通常是安全和有效的.
- 临床背景和替代疗法应与输血决定一起考虑.
- 这些建议旨在优化红细胞输血的使用,
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